Zicam Cold Remedy Homeopathic Rapid Melts. Reduces the severity and duration of cold symptoms when taken at the first sign of a cold, Sore throat, Stuffy nose, Sneezing, Coughing, Congestion. Zicam Cold Remedy is an over-the-counter homeopathic medicine that actually reduces the duration and severity of the common cold when taken at the first sign of cold symptoms. Quickly dissolves in your mouth without water Non-drowsy Non-habit forming No known drug interactions.