Thermoskin Arthritis Gloves are clinically proven to increase skin temperature and blood flow. This proven heat therapy helps relieve arthritic pain. Thermoskin Arthritis Gloves also provide light compression and support. This exclusive combination of clinically proven heat therapy and gentle support work together to bring natural relief from arthritic pain. Thermoskin Arthritis Gloves reduces the chances of swelling hands and ease the pain of sore joints. The gloves are also useful when doing household chores and gardening as they reduce soreness and swelling of the hands and fingers. This glove is not only helpful to arthritis sufferers, they are also helpful to anyone requiring gentle heat therapy to the joints of the hand. The complete outer layer of the gloves are a smooth nylon. There is an adjustable wrist closure for easy application and better fit. There is a right-hand and left hand glove in every pack. Trioxon Advantage: Thermoskin's exclusive Trioxon lining is soft and comfortable against your skin.  Trioxon captures your natural body heat for therapy and pain relief.  The three dimensional Trioxon lining provides insulation and wicking of moisture via air circulation.  This allows the skin to remain well oxygenated and comfortable for extended periods. Sizing Guide: Measure the circumference around the knuckles. Small 7 - 7 3/4 inches. Medium 8 - 9. Large 9 1/4 - 10 1/2. X-Large 10 3/4 - 11 1/2 inches. If in doubt on sizing for this product it is generally best to select the larger size.