Prime Time Direct Anti-Nausea Wristbands are meant to be worn on both the wrists to be fully effective. Each Anti-Nausea Wristband has a built in small downward facing button, meant to be worn on the inside of the wrist above the Nei-Kuan point. If one presses down on the button for a few minutes on both wrists simultaneously may alleviate all nauseous feelings instantly.