Kalmegh Or Andrographis Paniculata is a very important medicinal plant of traditional medicine system. It is used in Ayurveda, Siddha, Unani and Homeopathy. It is found growing wild throughout the plains and hills of tropical India, from Uttar Pradesh to Kerala, and also in Bangladesh, Pakistan and all South East Asian countries. All part of the plant is extremely bitter due to which plant is known as the king of bitter. This plant is called Hempedu Bumi (meaning bile of earth) in Malaysia. In Ayurveda, it is used in various ailments related vitiated Pitta / Kapha in Liver, Skin, and Intestine. As per Ayurvedic principle excess, Pitta cause disturbance in liver enzymes, which leads to inflammation in cells & thus viral load increases in the whole body. This raises body temperature & fever symptoms sets in, in such situation Kalmegh / Andrographis powder is useful. Andrographis paniculata helps in reducing fever and muscular & body pain. Kalmegh is especially useful for the liver. It exhibits hepato-protective and hepato-stimulative property. In traditional medicine system, aqueous extract of Andrographis is given for jaundice. Kalmegh or Andrographis powder is bitter in taste which helps to digest the food & prevents the formation of flatulency & toxic waste in the body. It activates the detoxifying function of the Liver & helps in cleansing Liver cells. Kalmegh has also shown blood cleansing & skin purifying properties. Kalmegh / Andrographis powder, when used with anti-oxidants like Amla, helps to eliminate free harmful radicles and regenerate Liver cells. Scientific Study of Kalmegh / Andrographis powder has shown the presence of Diterpenes (major component is Andrographolide) & flavonoids, which supports Anti-inflammation, analgesic & high blood glucose (postprandial) reducing properties.